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Tramadol : Uses, Side Effects, Dosage, Warnings

Tramadol is a pain reliever. Tramadol affects chemicals and receptors in the body that are associated with pain. Tramadol is used to relieve moderate to moderately severe pain. Tramadol is the generic of Ultram.

Ultram is a white, bitter, crystalline and odorless powder. Each Ultram tablet contains 50 mg of Ultram hydrochloride and is white in color.


Ultram has been given in single oral doses of 50, 100, 150 and 200 mg to patients with pain after surgical procedures and pain after oral surgery. In single-dose models of pain following oral surgery, pain relief was demonstrated in some patients at doses of 50 mg and 75 mg.

A dose of 100 mg of Ultram tended to provide pain relief superior to codeine sulfate 60 mg, but it was not effective as the combination of aspirin 650 mg with codeine phosphate 60 mg. In single-dose models of pain following surgical procedures, 150 mg provided pain relief generally equivalent to the combination of Darvocet N-100, with a tendency toward later peak effect.

Ultram has been studied in three long-term controlled trials involving a total of 820 patients, with 530 patients receiving Ultram. Patients with a variety of chronic painful conditions were studied in double-blind trials of one to three months duration.

Mean daily doses of about 250 mg of Ultram in divided doses were generally equivalent with five doses of Tylenol with Codeine #3 daily, five doses of aspirin 325 mg with codeine phosphate 30 mg daily, or two to three doses of Tylox daily.


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